Between 2009 and 2018, aeroplane accidents resulting from loss of control in flight (LOC-I) events were the leading cause of fatalities in commercial aviation. LOC-I accidents often have catastrophic results with very few, if any, survivors.  Boeing’s most recent Commercial Airplanes study (see below) shows that 1,181 lives (about 48% of total fatalities) were lost in 13 fatal LOC-I accidents worldwide over this period.

Similarly, an examination of the National Transportation Safety Board (NTSB) accident database reveals that LOC-I accidents represent more than 10% of all US-based commercial airlines accidents and more than 50% of all fatalities over the past two decades. 
 
Most shocking of all is that it is estimated that in more than 80% of these accidents, the aeroplane remained flyable; pilots lost control of functioning aeroplanes.